Endocrine Response to Exercise

Basic Sciences
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Overview

The endocrine response to exercise is the coordinated release of hormones that mobilises fuel, defends blood glucose and fluid balance during a session, and drives recovery and adaptation afterwards.

The endocrine system works with the nervous system to make this happen. For sport and exercise medicine (SEM) the physiology underpins:

  • Relative energy deficiency in sport (REDs), where low energy availability disturbs the hormonal axes
  • Exercise as treatment for type 2 diabetes, through improved insulin sensitivity
  • The endocrine changes seen with overtraining
  • Anti-doping, since many prohibited substances are hormones

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